Patients with high left atrial pressure exhibited significantly delayed apical kinetic energy fluid dynamics compared to normal subjects, which was closely associated with LV spherical remodelling.
Observational (n=61)
Does vector flow mapping detect abnormal intraventricular flow kinetic energy in patients with elevated filling pressure compared to normal subjects?
Vector flow mapping detects retarded apical kinetic energy fluid dynamics, which are closely associated with LV spherical remodelling in patients with high LA pressure.
AIMS: Recently developed vector flow mapping (VFM) enables evaluation of local flow dynamics without angle dependency. This study used VFM to evaluate quantitatively the index of intraventricular haemodynamic kinetic energy in patients with left ventricular (LV) diastolic dysfunction and to compare those with normal subjects. METHODS AND RESULTS: We studied 25 patients with estimated high left atrial (LA) pressure (pseudonormal: PN group) and 36 normal subjects (control group). Left ventricle was divided into basal, mid, and apical segments. Intraventricular haemodynamic energy was evaluated in the dimension of speed, and it was defined as the kinetic energy index. We calculated this index and created time-energy index curves. The time interval from electrocardiogram (ECG) R wave to peak index was measured, and time differences of the peak index between basal and other segments were defined as ΔT-mid and ΔT-apex. In both groups, early diastolic peak kinetic energy index in mid and apical segments was significantly lower than that in the basal segment. Time to peak index did not differ in apex, mid, and basal segments in the control group but was significantly longer in the apex than that in the basal segment in the PN group. ΔT-mid and ΔT-apex were significantly larger in the PN group than the control group. Multiple regression analysis showed sphericity index, E/E' to be significant independent variables determining ΔT apex. CONCLUSION: Retarded apical kinetic energy fluid dynamics were detected using VFM and were closely associated with LV spherical remodelling in patients with high LA pressure.
Nogami et al. (Fri,) conducted a observational in Elevated left atrial pressure / LV diastolic dysfunction (n=61). Elevated left atrial pressure vs. Normal subjects was evaluated on Time differences of the peak kinetic energy index between basal and other segments (ΔT-mid and ΔT-apex). Patients with high left atrial pressure exhibited significantly delayed apical kinetic energy fluid dynamics compared to normal subjects, which was closely associated with LV spherical remodelling.