Supra-annular and intra-annular self-expanding valves were associated with comparable device performance regarding hemodynamic structural and nonstructural dysfunction (P=0.6547).
Cohort
No
Do supra-annular self-expanding valves improve hemodynamic structural and nonstructural dysfunction compared to intra-annular valves in patients with small aortic annuli undergoing TAVR?
In patients with small aortic annuli undergoing TAVR, supra-annular and intra-annular self-expanding valves demonstrate comparable hemodynamic performance.
p-value: p=0.6547
Background: Transcatheter aortic valve replacement (TAVR) with self-expanding valves (SEVs) may have different outcomes with supra-annular valves (SAVs) or intra-annular valves (IAVs) in patients with small aortic annuli (SAA), but this topic remains underexplored. We aimed to evaluate outcomes between different SEVs, namely SAVs (CoreValve/Evolut R/PRO/PRO+/FX) vs. IAVs (Portico/Navitor). Methods: Single-center data with patients with SAA (maximum diameter <23 mm) who underwent TAVR from 2013 to 2023 with SEVs, followed by 1:1 propensity score matching (PSM). Results: = 0.6547) between patients who received SAVs and IAVs. For patients with SAA, TAVR with SEV devices is safe. Conclusions: IAVs and SAVs are associated with comparable device performance in terms of hemodynamic structural and nonstructural dysfunction. Randomized data are needed to validate these findings and guide informed device selection.
Sá et al. (Mon,) conducted a cohort in Small aortic annuli. Supra-annular valves (SAVs) vs. Intra-annular valves (IAVs) was evaluated on Hemodynamic structural and nonstructural dysfunction (p=0.6547). Supra-annular and intra-annular self-expanding valves were associated with comparable device performance regarding hemodynamic structural and nonstructural dysfunction (P=0.6547).