Background: Psoriasis is a chronic inflammatory skin disorder with diverse clinical and histopathological manifestations. Aims and Objectives: To evaluate the clinical and histomorphological variants of psoriasis and to study age and sex distribution. Materials and Methods: A prospective observational study was conducted on 80 clinically diagnosed cases of psoriasis. Skin biopsies were processed and examined histopathologically, and findings were correlated with clinical features. Histopathological examination confirmed 72 cases as psoriasis. Results: Males constituted 70.83% of cases, with peak incidence in 21–30 years (23.61%). The back was the most commonly involved site (34.72%). Plaques and erythema were the predominant clinical features (77.78% each). Histopathologically, parakeratosis (88.89%), acanthosis (86.11%), and dermal infiltration (97.22%) were the most frequent findings. Conclusion: Psoriasis shows significant clinicopathological variability, and correlation of clinical and histological features is essential for accurate diagnosis.
Gajjar et al. (Wed,) studied this question.