Follow-up of 65 patients with discrete subaortic stenosis showed development of aortic regurgitation and progressive membrane growth in both surgically resected and non-operated cases.
Cohort (n=65)
Does surgical resection of the membrane alter the evolutive aspects of discrete subaortic stenosis in children compared to no surgery?
Discrete subaortic stenosis has an evolutive character with progressive membrane growth and development of aortic regurgitation regardless of surgical resection, requiring long-term observation.
Discrete subaortic stenosis (DSS) is a frequent malformation easily diagnosed by echocardiography; surgical resection of the membrane is the most suitable treatment. However, some evolutive aspects of the lesion remain unexplained (the presence of aortic dysfunction, associated malformations, etc.). With a view to analyse these aspects, we have studied 65 patients with DSS and divided them into two groups: Group I, 37 patients without surgery, and Group II, 28 patients treated by resection of the membrane. During follow-up we observed: (a) development of aortic regurgitation in operated and non-operated cases; (b) frequent association of DSS with closed or closing ventricular septal defect; (c) the absence of DSS in neonates and (d) the progressive growth of the membrane. These aspects give this malformation an evolutive character that requires observation and management even after resection of the DSS.
Firpo et al. (Thu,) conducted a cohort in Discrete subaortic stenosis (DSS) (n=65). Surgical resection of the membrane vs. No surgery was evaluated on Development of aortic regurgitation and progressive growth of the membrane. Follow-up of 65 patients with discrete subaortic stenosis showed development of aortic regurgitation and progressive membrane growth in both surgically resected and non-operated cases.
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