CABG for stable angina yielded similar symptomatic improvements across age groups (p<0.0005), but elderly patients derived less benefit in quality of life and physical activity than younger patients.
Cohort (n=568)
Does primary isolated CABG improve quality of life, physical activity, and symptomatic status in patients with stable angina across different age groups?
While CABG improves symptomatic status across all ages, elderly patients (≥75 years) derive less benefit in terms of quality of life and physical activity compared to younger patients.
p-value: p=<0.0005
BACKGROUND: This study investigates changes of quality of life (QOL), physical activity (PA) and symptomatic status (NYHA) at one-year post-coronary artery bypass grafting (CABG). METHODS: Of 568 patients undergoing a primary isolated CABG for stable angina (NYHA or=75 years: 73 patients. RESULTS: There is a similar, significant decrease of NYHA class (1.4) for the three groups (p<0.0005). An overall significant improvement for QOL and PA is however different in the three subgroups. PA improvement is not significant in group C (p=0.74), significant in group B (p=0.005) and in group A (p<0.0005). For the QOL, group A shows a significant improvement for the five different domains, group B for two, and group C only for one domain. The visual analogue score as part of the QOL registration shows a significant increase for the three groups, however the improvement is minor with age, and between A (14.6) and C (9.1) this improvement is significantly different (p=0.047). CONCLUSIONS: Elderly patients have the same improvement of their symptomatic status as younger patients. However despite this improvement they have less benefit from CABG regarding to their quality of life and physical activity.
Markou et al. (Mon,) conducted a cohort in stable angina (n=568). Coronary artery bypass grafting (CABG) vs. Different age groups (<65, 65-74, ≥75 years) was evaluated on Changes in quality of life (QOL), physical activity (PA) and symptomatic status (NYHA) (p=<0.0005). CABG for stable angina yielded similar symptomatic improvements across age groups (p<0.0005), but elderly patients derived less benefit in quality of life and physical activity than younger patients.