In dilated cardiomyopathy, myocardial perfusion reserve, LV ejection fraction, and fibrosis are independently associated with aerobic exercise capacity (P<0.001).
Observational
Are cardiovascular magnetic resonance measures of coronary microvascular function associated with aerobic exercise capacity in patients with dilated cardiomyopathy?
In patients with dilated cardiomyopathy, coronary microvascular dysfunction, LV ejection fraction, and fibrosis assessed by CMR are independently associated with aerobic exercise capacity.
p-value: p=<0.001
BACKGROUND: Aerobic exercise capacity is an independent predictor of mortality in dilated cardiomyopathy (DCM), but the central mechanisms contributing to exercise intolerance in DCM are unknown. The aim of this study was to characterize coronary microvascular function in DCM and determine if cardiovascular magnetic resonance (CMR) measures are associated with aerobic exercise capacity. METHODS: . RESULTS: = 0.531, P < 0.001). CONCLUSION: In comparison to controls, DCM patients have lower stress myocardial blood flow and MPR. In DCM, MPR, LV ejection fraction, and fibrosis are independently associated with aerobic exercise capacity.
Dattani et al. (Mon,) conducted a observational in Dilated cardiomyopathy (DCM). Coronary microvascular dysfunction (CMR measures) vs. Controls was evaluated on Aerobic exercise capacity (p=<0.001). In dilated cardiomyopathy, myocardial perfusion reserve, LV ejection fraction, and fibrosis are independently associated with aerobic exercise capacity (P<0.001).
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