Medications such as calcium channel blockers, beta blockers, and nitroglycerin, along with ECG alterations like atrioventricular block, may impact the interpretation of myocardial perfusion scans.
How do ECG alterations and specific medications impact the interpretation of SPECT myocardial perfusion scans?
Certain ECG patterns and medications can significantly impact the interpretation of SPECT myocardial perfusion scans, necessitating awareness by referring clinicians.
Coronary artery disease (CAD) is the leading cause of death followed by cancer, in men and women. With risk factors being endemic and the increasing costs of healthcare for management and treatment, myocardial perfusion imaging (MPI) finds a central role in risk stratification and prognosis for CAD patients, but it comes with its limitations in that the referring clinician and managing team must be aware of and use at their advantage. This narrative review examines the utility of myocardial perfusion scans in the diagnosis and management of patients with ECG alterations such as atrioventricular block (AVB), and medications including calcium channel blockers (CCB), beta blockers (BB), and nitroglycerin which may impact the interpretation of the exam. The review analyzes the current evidence and provides insights into the limitations, delving into the reasons behind some of the contraindications to MPI.
Sidrak et al. (Wed,) conducted a review in Coronary artery disease (CAD). Medications (CCB, BB, nitroglycerin) and ECG alterations (AVB) was evaluated. Medications such as calcium channel blockers, beta blockers, and nitroglycerin, along with ECG alterations like atrioventricular block, may impact the interpretation of myocardial perfusion scans.
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