Dobutamine stress echocardiography criteria were evaluated for predicting true-severe aortic stenosis and death in a prospective cohort of 186 patients with low-flow, low-gradient aortic stenosis.
Cohort (n=186)
BACKGROUND: In the American College of Cardiology/American Heart Association guidelines, patients are considered to have true-severe stenosis when the mean gradient (MG) is ≥40 mm Hg with an aortic valve area (AVA) ≤1 cm OBJECTIVES: The aim of this study was to assess the value of these criteria to predict the presence of true-severe AS and the occurrence of death in patients with low-flow, low-gradient aortic stenosis (LF-LG AS). METHODS: One hundred eighty-six patients with low left ventricular ejection fraction (LVEF) LF-LG AS were prospectively recruited and underwent DSE, with measurement of the MG, AVA, and the projected AVA (AVA RESULTS: Peak stress MG ≥40 mm Hg, peak stress AVA ≤1 cm CONCLUSIONS: In patients with low LVEF LF-LG AS, the DSE criteria of a peak stress MG ≥40 mm Hg, or the composite of a peak stress MG ≥40 mm Hg and a peak stress AVA ≤1 cm
“Annabi et al provided strong evidence that these criteria are neither sensitive nor specific for identifying TSAS. Furthermore, because these parameters do not predict survival in medically treated patients, they are not ideal tools for identifying candidates for AVR.”
Annabi et al. (Mon,) conducted a cohort in Low-flow, low-gradient aortic stenosis (LF-LG AS) (n=186). Dobutamine Stress Echocardiography (DSE) was evaluated on Presence of true-severe AS and occurrence of death. Dobutamine stress echocardiography criteria were evaluated for predicting true-severe aortic stenosis and death in a prospective cohort of 186 patients with low-flow, low-gradient aortic stenosis.
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