June 5, 2011
View Full PaperTranscatheter Aortic-Valve Implantation — At What Price?
Key Result
Transcatheter aortic-valve implantation has developed rapidly as an alternative to surgical valve replacement, with two relatively mature technologies in clinical use.
Structured PICO
I
Intervention
Transcatheter aortic-valve implantation (TAVI)
Discusses the historical development and clinical emergence of transcatheter aortic-valve implantation technologies.
Abstract
In 2000, Bonhoeffer et al. described transvenous placement of a pulmonary-valve prosthesis and speculated that similar technology might be used in other cardiac valves, including the aortic position.1 Two years later, the first transcatheter insertion of an aortic-valve prosthesis was performed by Cribier et al.2 Transcatheter aortic-valve implantation has developed rapidly, and two relatively mature technologies are in clinical use: the SAPIEN Transcatheter Heart Valve (Edwards Lifesciences) and the CoreValve Revalving System (Medtronic). In contrast to surgical valve replacement, in which the diseased, calcified cusps are removed, these and other catheter-based techniques in development rely on forcibly spreading the stenotic . . .