January 1, 2019Theranostics244 citationsOpen Access

Dioscin Alleviates Crystalline Silica-Induced Pulmonary Inflammation and Fibrosis through Promoting Alveolar Macrophage Autophagy

SDSitong DuJilin Agricultural University CLChao LiEli Lilly (United States)YLYiping LuEast China University of Science and Technology

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Abstract

Dioscin promoting autophagy leads to reduced CS-induced mitochondria-dependent apoptosis and cytokine production in AMs, which may provide concrete molecular mechanism for the therapy of silicosis.

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Du et al. (Tue,) studied this question.

synapsesocial.com/papers/6a62204fcd947529a989b68a https://doi.org/https://doi.org/10.7150/thno.29682

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