Over 15 years of follow-up, poliomyelitis survivors demonstrated only a modest decline in neuromuscular function, with late deterioration symptoms associated with the magnitude of residual deficits.
Cohort
In polio survivors, late deterioration symptoms are related to baseline residual deficits rather than ongoing functional decline over 15 years.
A population-based cohort of poliomyelitis survivors was established and followed for 15 years (mean time since poliomyelitis was 40 years). Over time, the cohort demonstrated only a modest decline in function as measured by strength measurements, electrophysiologic assessments, and timed functional tasks. There was no association between symptoms of late deterioration and magnitude of decline. Rather, the presence of these symptoms was associated with the magnitude of the residual deficits.
Sorenson et al. (Tue,) conducted a cohort in Prior poliomyelitis. Prior poliomyelitis was evaluated on Neuromuscular function (strength measurements, electrophysiologic assessments, and timed functional tasks). Over 15 years of follow-up, poliomyelitis survivors demonstrated only a modest decline in neuromuscular function, with late deterioration symptoms associated with the magnitude of residual deficits.