Adrenal vein sampling showed only 54% concordance with computed tomography, supporting its superiority for subtype differentiation of primary hyperaldosteronism.
Observational (n=48)
No
Does adrenal vein sampling improve subtype differentiation compared to computed tomography in patients with primary hyperaldosteronism?
Adrenal vein sampling has low concordance with computed tomography, supporting its superiority for accurate subtype differentiation in primary hyperaldosteronism.
HYPOTHESIS: Adrenal vein sampling is superior to computed tomography for subtype differentiation of primary hyperaldosteronism. DESIGN: Retrospective review. SETTING: University medical center. PATIENTS: Forty-eight patients (32 men and 16 women) with biochemically confirmed primary hyperaldosteronism. MAIN OUTCOME MEASURES: We compared demographic factors, results of biochemical and imaging studies (computed tomography and adrenal vein sampling), therapy, and patient outcomes. RESULTS: Mean +/- SEM adrenal nodule size was 1.54 +/- 0.2 cm. Adrenal vein sampling was performed in 41 (85%) of 48 patients, and it was successful in 39 (95%) of those 41 patients. Concordance between computed tomography and adrenal vein sampling was observed in 22 (54%) of the 41 patients. Thirty-two patients underwent successful laparoscopic adrenalectomy. There was 1 complication and no deaths. All 32 patients were cured of hypokalemia. CONCLUSION: Adrenal vein sampling is superior to image-based techniques for subtype differentiation of primary hyperaldosteronism.
Fiemu E. Nwariaku (Mon,) conducted a observational in Primary hyperaldosteronism (n=48). Adrenal vein sampling vs. Computed tomography was evaluated on Concordance between computed tomography and adrenal vein sampling. Adrenal vein sampling showed only 54% concordance with computed tomography, supporting its superiority for subtype differentiation of primary hyperaldosteronism.