For patients under 65 with severe aortic stenosis and current durability data, should the first valve be surgical to protect lifetime options, or transcatheter with a plan to reintervene?

Active since Jan 2022

Heat

Patients affected

incident cases of severe AS / year

0Estimate

in a community of ~100,000 residents, with ~40% remaining undertreated

Resolution

No fixed date yet

Sources

How this gets settled

Resolving trial — not yet identified

Resolution

No fixed date yet

What settles itResolving-trial readout

The debate

Surgery firstvsTAVR first

Who could settle it

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Who could fund or run it

Academia

Funders

Industry

Institutions that could fund, run, or adopt

Who this affects

Affected rangeEstimate

2–3

≈1Kincident cases of severe AS / yearEstimate

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Sources & verification

48linked & dated sources

VerifiedConfirmed against a primary source (registry API or dual-model citation gate).EstimateA computed estimate (e.g. comparable-based cost or modeled range), not a measured value.Scan-reportedReported by the scan and linked to its source — not yet independently verified.