| 1 | Cardiopulmonary Exercise Testing Journal of the American College of Cardiology · Guazzi M et al. | Sep 1 | | Yes (JACC) | — | Yes (TWiC) | — | — |
| 2 | Left Ventricular Unloading in High-Risk Percutaneous Coronary Intervention New England Journal of Medicine · Perera D et al. | Mar 29 | | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 3 | High Thrombus Burden in Patients With COVID-19 Presenting With ST-Segment Elevation Myocardial Infarction Journal of the American College of Cardiology · Choudry F et al. | Jul 14 | | Yes (JACC) | — | — | — | — |
| 4 | Defining Cardiovascular Endpoints in Oncology Trials: Challenges and Opportunities: A Scientific Statement From the American Heart Association Circulation · Barac A et al. | Jun 15 | | Yes (Circulation) | — | — | — | — |
| 5 | Peripartum Cardiomyopathy Journal of the American College of Cardiology · Davis M et al. | Jan 1 | | Yes (JACC) | — | Yes (TWiC) | — | — |
| 6 | High-sensitivity C-reactive protein, statin therapy, and risks of atrial fibrillation: an exploratory analysis of the JUPITER trial European Heart Journal · Peña J et al. | Dec 20 | | Yes (European Heart Journal) | — | — | — | — |
| 7 | Resistance Training, Aerobic Activity, Television Viewing, and Risk of Major Cardiovascular Events in U.S. Women Journal of the American College of Cardiology · Zhang T et al. | Jun 1 | | Yes (ACC Journal Scan) | — | — | — | — |
| 8 | Mavacamten in Nonobstructive Hypertrophic Cardiomyopathy New England Journal of Medicine | Jun 17 | | Yes (NEJM) | — | — | — | — |
| 9 | Artificial intelligence in the diagnosis and management of arrhythmias European Heart Journal · Nagarajan V et al. | Jul 26 | | Yes (European Heart Journal) | — | — | — | — |
| 10 | Left Atrial Appendage Closure or Anticoagulation for Atrial Fibrillation New England Journal of Medicine · Doshi S et al. | Mar 28 | | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 11 | Conservative Oxygen for Unresponsive Patients after Cardiac Arrest New England Journal of Medicine · Group T et al. | Jun 10 | | Yes (NEJM) | — | — | — | — |
| 12 | Case 16-2026: A 14-Year-Old Girl with Hypertension New England Journal of Medicine · Osborn R et al. | Jun 10 | | Yes (NEJM) | — | — | — | — |
| 13 | Sisyphean Task of Cardiovascular Prevention: Real Gains, Unequal Progress Circulation · Ziaeian B et al. | Jun 15 | | Yes (Circulation) | — | — | — | — |
| 14 | The Cardiovascular Cost of Medicaid Cuts Under H.R. 1 Circulation · Narasimmaraj P et al. | Jun 15 | | Yes (Circulation) | — | — | — | — |
| 15 | Heart Failure With Preserved Ejection Fraction and Diabetes Journal of the American College of Cardiology · McHugh K et al. | Feb 1 | | Yes (JACC) | — | — | — | — |
| 16 | Sirolimus-Coated Balloon Angioplasty for Infrainguinal Artery Disease New England Journal of Medicine · Barco S et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 17 | Cardiovascular Disease Mortality in Asian Americans Journal of the American College of Cardiology · Jose P et al. | Dec 1 | | Yes (JACC) | — | — | — | — |
| 18 | Effect of APOC3 Inhibition with Olezarsen on Coronary Atherosclerosis: Essence–TIMI 73b Imaging Study Circulation · Marston N et al. | Mar 30 | — | Yes (Circulation) | — | Yes (TWiC) | — | — |
| 19 | Discontinuation of Beta-Blocker Therapy after Myocardial Infarction New England Journal of Medicine · Choi K et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 20 | Angiotensin-Converting Enzyme Inhibitors in Hypertension Journal of the American College of Cardiology · Messerli F et al. | Apr 1 | | Yes (JACC) | — | — | — | — |
| 21 | Mavacamten in Adolescents with Obstructive Hypertrophic Cardiomyopathy New England Journal of Medicine · Rossano J et al. | Mar 29 | | Yes (NEJM) | — | — | — | — |
| 22 | Left Ventricular Noncompaction Journal of the American College of Cardiology · Arbustini E et al. | Aug 1 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 23 | Consideration of a New Definition of Clinically Relevant Myocardial Infarction After Coronary Revascularization Journal of the American College of Cardiology · Moussa I et al. | Oct 1 | — | Yes (JACC) | — | Yes (TWiC) | — | — |
| 24 | Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease New England Journal of Medicine · Lee Y et al. | Mar 28 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 25 | Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism New England Journal of Medicine · Rosenfield K et al. | Mar 28 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 26 | IVUS-Guided versus Angiography-Guided PCI in Unprotected Left Main Coronary Disease New England Journal of Medicine · Testa L et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 27 | Intravascular Ultrasound–Guided or Angiography-Guided Complex High-Risk PCI New England Journal of Medicine · Diletti R et al. | Mar 30 | — | Yes (NEJM) | — | Yes (TWiC) | — | — |
| 28 | Multicenter Randomized Trial Evaluating the Efficacy of Cilostazol on Ischemic Vascular Complications After Drug-Eluting Stent Implantation for Coronary Heart Disease Journal of the American College of Cardiology · Suh J et al. | Jan 1 | | Yes (JACC) | — | — | — | — |
| 29 | Early Surgery for Asymptomatic Aortic Stenosis at 10 Years New England Journal of Medicine | Jun 10 | | Yes (NEJM) | — | — | — | — |
| 30 | Strategies for Optimizing Heart Failure Care in the Older Adult: A Scientific Statement From the American Heart Association Circulation · Lewsey S et al. | Jun 18 | — | Yes (Circulation) | — | — | — | — |
| 31 | Mechanical CPR Device Use and Cardiac Arrest Survival in EMS Agencies Circulation · Chan P et al. | Jun 18 | — | Yes (Circulation) | — | — | — | — |
| 32 | Vacuolar H + -ATPase Preserves Cardiolipin Homeostasis Through the Lysosomal-Mitochondrial Axis to Restrain Cardiac Aging Circulation · Tie H et al. | Jun 17 | — | Yes (Circulation) | — | — | — | — |
| 33 | All-Cause Mortality and Cardiovascular Outcomes With Prophylactic Steroid Therapy in Duchenne Muscular Dystrophy Journal of the American College of Cardiology · Schram G et al. | Jan 23 | | Yes (JACC) | — | — | — | — |
| 34 | Association between Triglyceride-glucose (TyG) Index and Risk of Stroke Recurrence and Mortality: A Systematic Review and Meta-analysis (P4-5.001) Neurology · Malik D et al. | Jun 9 | | — | — | — | — | — |
| 35 | Disparities in Cardiovascular Medicine: Evidence Is Not Enough, Policy Change Is Essential Circulation · Brandt E et al. | Jun 15 | — | Yes (Circulation) | — | — | — | — |
| 36 | Pharmacoequity and the Promise of GLP-1 Therapies in Cardiovascular Disease Circulation · Essien U et al. | Jun 15 | — | Yes (Circulation) | — | — | — | — |
| 37 | Sirolimus-Eluting Balloon With Provisional Stenting Versus Systematic Drug-Eluting Stent Implantation to Treat De Novo Coronary Lesions: A Randomized, Open-Label, Noninferiority Trial Circulation · Spaulding C et al. | Jun 15 | — | Yes (Circulation) | — | — | — | — |
| 38 | Clinical Guidelines, Market Forces, and Health Disparities Circulation · Kohli‐Lynch C et al. | Jun 15 | — | Yes (Circulation) | — | — | — | — |
| 39 | Galectin-3 Regulates Smooth Muscle Contraction and Blood Pressure by Modulating Ca V 1.2 Channel Function Circulation · Loh K et al. | Jun 15 | — | Yes (Circulation) | — | — | — | — |
| 40 | Mortality Benefit of Rivaroxaban Plus Aspirin in Patients With Chronic Coronary or Peripheral Artery Disease Journal of the American College of Cardiology · Eikelboom J et al. | Jun 28 | | Yes (JACC) | — | — | — | — |
| 41 | Including measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP European Heart Journal · Matsushita K et al. | Oct 1 | | Yes (European Heart Journal) | — | — | — | — |
| 42 | Chronic Thromboembolic Pulmonary Hypertension Journal of the American College of Cardiology · Papamatheakis D et al. | Oct 26 | | Yes (JACC) | — | — | — | — |
| 43 | Artificial intelligence-enabled electrocardiogram for left ventricular diastolic dysfunction and long-term risk of new-onset atrial fibrillation European Heart Journal · Tsaban G et al. | Oct 1 | | Yes (European Heart Journal) | — | — | — | — |
| 44 | Severe Aortic Stenosis and Coronary Artery Disease—Implications for Management in the Transcatheter Aortic Valve Replacement Era Journal of the American College of Cardiology · Goel S et al. | May 1 | | Yes (JACC) | — | — | — | — |
| 45 | Metabolically-Healthy Obesity and Coronary Artery Calcification Journal of the American College of Cardiology · Chang Y et al. | Apr 30 | | Yes (JACC) | — | — | — | — |
| 46 | Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction Journal of the American College of Cardiology · Tromp J et al. | Aug 27 | | Yes (JACC) | — | — | — | — |
| 47 | Clinical Outcomes of GLP-1 Receptor Agonist and SGLT2 Inhibitor Combination Therapy in Heart Failure: A Real-World Propensity-Matched TriNetX Analysis Biomedicines · Ahmed F et al. | Jun 17 | | — | — | — | — | — |
| 48 | PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction European Heart Journal · Dalt L et al. | Jun 24 | — | Yes (European Heart Journal) | — | — | — | — |
| 49 | Relationship of PCSK9 and Urinary Thromboxane Excretion to Cardiovascular Events in Patients With Atrial Fibrillation Journal of the American College of Cardiology · Pastori D et al. | Sep 1 | — | Yes (JACC) | — | — | — | — |
| 50 | The PCSK9-LDL Receptor Axis and Outcomes in Heart Failure Journal of the American College of Cardiology · Bayés‐Genís A et al. | Oct 1 | — | Yes (JACC) | — | — | — | — |