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Hot Research Today
Papers from every journal, all in one place。 创建自定义信息流。
RCT · n=78410 次提及Trending on X
7月30日Oosterom-EijmaelJAMA
Dapagliflozin before elective cardiac surgery reduces 7-day AKI ~46% versus placebo.
Perioperative dapagliflozin reduces postoperative AKI; extends SGLT2i use to cardiac surgery prevention.
DWDr. Wolfgang C. Winkelmayer
nephrologist, Baylor College of Medicine
Hereon, investigators should aim to better understand the mechanism(s) by which SGLT2 inhibitors reduce the risk of AKI among patients undergoing elective cardiac surgery as well as those with type 2 diabetes, heart failure, and chronic kidney disease treated with SGLT2 inhibitors longer-term. Moreover, they should briskly and rigorously conduct randomized, placebo-controlled clinical trials of SGLT2 inhibitors in established AKI, aiming to arrest or attenuate its evolution and/or hasten its recovery.
RCT · n=2796 次提及
7月30日PüntmannNature Communications
Losartan plus prednisolone fails to improve LVEF over placebo in post-COVID syndrome.
First RCT of anti-inflammatory therapy in post-COVID cardiac involvement; leaves open whether losartan plus prednisolone improves symptoms or imaging.
ARAnonymous Reviewer
Peer Reviewer, Springer Nature
The manuscript is well written, the introduction and aim are easy to follow, and the results are somewhat easy to follow. Notwithstanding, this reviewer is somewhat uneasy about the presentation of the changes in anatomical and functional measurements.
systematic_review · n=108 次提及Trending on X
7月30日RamzyCureus
GLP-1 RAs linked to lower incident AF and post-ablation recurrence based on low-confidence evidence.
Cautions against over-relying on overlapping low-confidence meta-analyses; leaves open need for independent high-quality trials on GLP-1 RAs and AF.
DLDr. Lee
Clinical Pharmacy, PlexusDx
Semaglutide is not absolutely contraindicated in atrial fibrillation, but individual cardiac history, current medications, and AFib severity must guide the decision. Recent data shows GLP-1 receptor agonists may offer cardiovascular benefits in certain patient populations, yet AFib presents unique arrhythmia-specific considerations that require personalized evaluation.
Cohort Study1 次提及
7月30日EkmejianHeart Lung and Circulation
A Report from the Second Year of the Prospective Australasian National Bifurcation Coronary Intervention Outcomes Registry (ABC Registry)
Prospective registry reports outcomes of bifurcation coronary interventions, indicating clinical pathways for optimal care.
Cohort Study1 次提及
7月30日FangHeart Lung and Circulation
Enduringly Poor Outcomes in Medically Managed Patients With Non-ST Elevation Myocardial Infarction in a Contemporary Australian Cohort 2013–2021
Observational study reveals poor outcomes in medically managed non-ST elevation myocardial infarction patients, indicating the need for improved strategies.
Cohort Study1 次提及
7月30日KimHeart Lung and Circulation
Thrombolysis for ST-Elevation Myocardial Infarction in the Modern Era: A Retrospective Review of a High-Volume Regional Tertiary Centre
Retrospective review assesses thrombolysis outcomes in patients with ST-elevation myocardial infarction, indicating clinical implications.
RCT · n=1291 次提及Trending on X
8月1日SattarFuture Cardiology
Center-based cardiac rehabilitation achieved superior gains in exercise capacity and better blood pressure control compared to home-based rehabilitation (P<0.001).
Home-based CR may expand access without loss of benefit; extends RCT evidence to Iranian settings.
meta-analysis · n=8701 次提及Trending on X
7月31日DengMedicine
Atenolol significantly reduced the incidence of postoperative atrial fibrillation in adults undergoing cardiac surgery (RR 0.55; 95% CI 0.32-0.93; P=0.03).
Atenolol may reduce POAF after cardiac surgery; extends limited prior RCT data on this specific beta-blocker.
cohort · n=1573 次提及Trending on X
8月1日MatsumotoJournal of Cardiovascular Electrophysiology
An LLM-based staged extraction framework achieved comparable discrimination to a CNN-based model for localizing PVC origins from 12-lead ECGs (AUC 0.720 vs. 0.712).
May support interpretable ECG analysis for PVC localization; leaves open prospective validation before clinical use.
cohort · n=1,3301 次提及Trending on X
7月30日DingHarvard University
Improving Life's Simple 7 score is linked to a ~46% lower risk of recurrent CHD.
LS7 improvements may lower recurrent CHD risk; extends secondary prevention evidence but leaves causality open without RCTs.
