Figure S11 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

Puntos clave

• TGFβ inhibition during radiotherapy significantly increases immune cell infiltration in tumors.
• Distinct tumor transcriptional signatures are observed in Ewing sarcomas from different mouse models.
• Inhibition leads to decreased metastases, indicating a potential therapeutic strategy.
• Study used hu-cD34+ and NSG mouse models to evaluate responses to radiotherapy.