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The absolute risk was estimated using different combinations of PRS and NGRF risk levels. PRS was classified into three risk groups according to percentile distributions (0-20%: low, 20-80%: mid, 80-100%: high). NGRF score was classified into two groups divided at median (0-50%: low, 50-100%: high). The dotted lines represent the average risks. (A) Lifetime absolute risk (B) 5-year absolute risk
Choi et al. (Mon,) studied this question.