August 14, 2024

Ultrashort-echo time magnetization transfer (UTE-MT) for brain iron imaging

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Resumen

We have established a novel 3D dual-echo UTE-MT imaging method to assess hyperintense T1w signal in iron-rich brain areas by eliminating the ultra-short T2 constituents of the myelin signal via the magnetization transfer (MT) technique. Our preliminary results show improved positive image contrast in deep brain areas such as the substantia nigra (SN) and the LC. Other iron-rich areas in the basal ganglia (globus pallidus and putamen) also show improved contrast.

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Monsivais et al. (Wed,) studied this question.

synapsesocial.com/papers/68e5c61db6db64358755c6e1 https://doi.org/https://doi.org/10.58530/2023/0120

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2Fat-suppressed ultrashort echo time magnetization transfer (UTE-MT) modeling via subtraction of fat-selective image2025
3<scp> T <sub>1</sub> </scp> ‐weighted <scp>fMRI</scp> in mouse visual cortex using an iron oxide nanoparticle contrast agent and <scp>UTE</scp> imaging at 9.4 T2025 · 2 citations
4Comparison of Myelin Fraction Maps Acquired with mcUTE, T2 Relaxation and Magnetization Transfer2025
5Ultra‐low‐field magnetization transfer imaging at 0.055T with low specific absorption rate2024 · 2 citations

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