TABLE 1 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency

LP-184 is effective in patient-derived solid tumor models. LP-184 ex vivo potency in a 5-day cell proliferation assay compared with olaparib in a panel of HRD patient-derived tumor graft models representing multiple solid tumor types