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May 6, 2024Open Access

TABLE 1 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency

Aditya Kulkarni Jianli Zhou Neha Biyani Umesh Kathad Partha P. Banerjee Shiv Srivastava Zsombor Prucsi Kamil Solarczyk Kishor Bhatia Reginald B. Ewesuedo Panna Sharma

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Abstract

LP-184 is effective in patient-derived solid tumor models. LP-184 ex vivo potency in a 5-day cell proliferation assay compared with olaparib in a panel of HRD patient-derived tumor graft models representing multiple solid tumor types

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Cite This Study

Kulkarni et al. (2024) studied this question.

synapsesocial.com/papers/68e6b5fbb6db64358763774a https://doi.org/10.1158/2767-9764.25757498.v1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1TABLE 1 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency2024
2FIGURE 2 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency2024
3TABLE 2 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency2024
4TABLE 2 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency2024
5Supplementary Figure S5 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency2024

Supplementary Figure S5 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency2024
Supplementary Figure S11 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency2024
Supplementary Figure S11 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency2024