Mp61-19 Incidence of Erectile Dysfunction and Testosterone Deficiency in Testicular Cancer Survivors

You have accessJournal of UrologyPenile & Testicular Cancer II (MP61)1 May 2024MP61-19 INCIDENCE OF ERECTILE DYSFUNCTION AND TESTOSTERONE DEFICIENCY IN TESTICULAR CANCER SURVIVORS Kshitij Pandit, Paul Riviere, Tyler Nelson, Margaret Meagher, Dhruv Puri, Nuphat Yodkhunnatham, Kylie M. Morgan, Leah N. Deshler, Elizabeth A. Duran, Daniel Sabater-Minarim, Juan Javier-Desloges, Amirali Salmasi, Rana R. Mckay, Frederick Millard, Tung-Chin Hsieh, Darshan P. Patel, Brent S. Rose, Daniel Herchenhorn, and Aditya Bagrodia Kshitij PanditKshitij Pandit , Paul RivierePaul Riviere , Tyler NelsonTyler Nelson , Margaret MeagherMargaret Meagher , Dhruv PuriDhruv Puri , Nuphat YodkhunnathamNuphat Yodkhunnatham , Kylie M. MorganKylie M. Morgan , Leah N. DeshlerLeah N. Deshler , Elizabeth A. DuranElizabeth A. Duran , Daniel Sabater-MinarimDaniel Sabater-Minarim , Juan Javier-DeslogesJuan Javier-Desloges , Amirali SalmasiAmirali Salmasi , Rana R. MckayRana R. Mckay , Frederick MillardFrederick Millard , Tung-Chin HsiehTung-Chin Hsieh , Darshan P. PatelDarshan P. Patel , Brent S. RoseBrent S. Rose , Daniel HerchenhornDaniel Herchenhorn , and Aditya BagrodiaAditya Bagrodia View All Author Informationhttps://doi.org/10.1097/01.JU.0001009536.58867.87.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Testicular cancer (TC) survivors have excellent oncologic outcomes, but may suffer from long-term adverse treatment related health outcomes for the remainder of their lives. This project aims to characterise the incidence of men's health disorders, specifically focusing on erectile dysfunction (ED) and testosterone deficiency (TD) in TC survivors. METHODS: We conducted a retrospective cohort study of US veterans diagnosed with TC from 1990-2021. These were compared to an age-matched control group of US veterans without diagnosis of TC. ED and TD were defined either by the presence of diagnosis codes or at least a 6-months prescription for medications treating these conditions. Time was measured from date of TC diagnosis (for TC patients, and matched TC patient date for the corresponding non-cancer controls). Association between outcomes and a diagnosis of TC or receipt of chemotherapy was evaluated using multivariable Cox regression models. RESULTS: 2022 TC patients were compared to 7595 non-cancer controls. TC patients were significantly more likely to experience ED (Hazard Ratio (HR) 2.97, 95% confidence interval (CI) 2.71-3.25, p<0.001) and TD (HR 5.59, 95% CI 4.88-6.40, p<0.001).However, within the TC group, there was no significant difference in the incidence of ED and TD when stratified by receipt of chemotherapy (p=0.743 and p=0.561, respectively). CONCLUSIONS: ED and TD arise more commonly and earlier in the lives of TC survivors. It is important for treating physicians to screen for these diseases to provide timely and appropriate care. Download PPTDownload PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1019 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Kshitij Pandit More articles by this author Paul Riviere More articles by this author Tyler Nelson More articles by this author Margaret Meagher More articles by this author Dhruv Puri More articles by this author Nuphat Yodkhunnatham More articles by this author Kylie M. Morgan More articles by this author Leah N. Deshler More articles by this author Elizabeth A. Duran More articles by this author Daniel Sabater-Minarim More articles by this author Juan Javier-Desloges More articles by this author Amirali Salmasi More articles by this author Rana R. Mckay More articles by this author Frederick Millard More articles by this author Tung-Chin Hsieh More articles by this author Darshan P. Patel More articles by this author Brent S. Rose More articles by this author Daniel Herchenhorn More articles by this author Aditya Bagrodia More articles by this author Expand All Advertisement PDF downloadLoading ...