Mp01-10 the Landscape of Racial and Ethnic Disparity in Testicular Cancer Stage Presentation: A National Hospital-Based Study

You have accessJournal of UrologyPenile & Testicular Cancer I (MP01)1 May 2024MP01-10 THE LANDSCAPE OF RACIAL AND ETHNIC DISPARITY IN TESTICULAR CANCER STAGE PRESENTATION: A NATIONAL HOSPITAL-BASED STUDY Khalid Y. Alkhatib, Ian Mitchell Harmatz, John Pluta, Morgan Leff, Brian D. Cortese, Nathaniel McLaughlan, Thomas Guzzo, Katherine L. Nathanson, David J. Vaughn, Phillip M. Pierorazio, and Daniel J. Lee Khalid Y. AlkhatibKhalid Y. Alkhatib , Ian Mitchell HarmatzIan Mitchell Harmatz , John PlutaJohn Pluta , Morgan LeffMorgan Leff , Brian D. CorteseBrian D. Cortese , Nathaniel McLaughlanNathaniel McLaughlan , Thomas GuzzoThomas Guzzo , Katherine L. NathansonKatherine L. Nathanson , David J. VaughnDavid J. Vaughn , Phillip M. PierorazioPhillip M. Pierorazio , and Daniel J. LeeDaniel J. Lee View All Author Informationhttps://doi.org/10.1097/01.JU.0001008660.87408.90.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Testicular cancer's (TC) high curability presents a significant challenge in assessing racial and ethnic disparities using mortality outcomes. Examining the stage of presentation may provide valuable insights into existing disparities. We used the National Cancer Database to evaluate racial and ethnic differences in TC stage of presentation. METHODS: We analyzed TC patients between 2004 and 2016 using multivariable logistic regression analysis to investigate predictors of disease stage. Using a multivariable multinomial logistic regression, we calculated the marginal predicted probability for stage I, II, and III disease. We then estimated the adjusted risk difference (ARD) for each racial and ethnic group vs non-Hispanic white (NHW). RESULTS: We identified 70,757 TC patients for analysis. Descriptors and predictors are found in Table 1. Non-Hispanic black race (NHB) (OR: 1.21, 95%CI: 1.09, 1.35, p<0.01) and Hispanic ethnicity (OR: 1.16, 95%CI: 1.09, 1.23, p<0.01) were significant predictors of late stage (stage II/III) presentation. We also found a significant decrease in the adjusted predicted probability for stage I presentation in both NHB (ARD: -0.04, 95%CI: -0.06, -0.02, p<0.01) and Hispanics (ARD: -0.03, 95%CI: -0.04 , -0.01 , p<0.01) and a significant increase in the adjusted predicted probability of stage III presentation in NHB (ARD: 0.03, 95%CI: 0.01, 0.05, p<0.01), Hispanics (ARD: 0.03, 95%CI: 0.02, 0.04, p<0.01), and Asian American and Native Hawaiian/Pacific Islanders (AANHPI) (ARD: 0.02, 95%CI: 0.00, 0.04, p=0.02) compared to NHW (Figure 1). CONCLUSIONS: As compared to NHW, NHB and Hispanic are more likely to present with late stage disease and less likely to present with stage I disease. Additionally, NHB, Hispanics, and AANHPI are more likely to present with stage III disease. Our findings indicate an under-recognition of early stage TC in non-whites. Further investigating the drivers behind this could significantly impact TC care at the national level. Download PPT Source of Funding: N/A © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e5 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Khalid Y. Alkhatib More articles by this author Ian Mitchell Harmatz More articles by this author John Pluta More articles by this author Morgan Leff More articles by this author Brian D. Cortese More articles by this author Nathaniel McLaughlan More articles by this author Thomas Guzzo More articles by this author Katherine L. Nathanson More articles by this author David J. Vaughn More articles by this author Phillip M. Pierorazio More articles by this author Daniel J. Lee More articles by this author Expand All Advertisement PDF downloadLoading ...