Pd13-04 Active Surveillance for Prostate Cancer in “Real-World” Setting: Exploring Racial Disparities in Surveillance Intensity and Cancer Control Outcomes

You have accessJournal of UrologyProstate Cancer: Localized: Active Surveillance I (PD13)1 May 2024PD13-04 ACTIVE SURVEILLANCE FOR PROSTATE CANCER IN "REAL-WORLD" SETTING: EXPLORING RACIAL DISPARITIES IN SURVEILLANCE INTENSITY AND CANCER CONTROL OUTCOMES Giuseppe Chiarelli, Alex Stephens, Marco Finati, Giuseppe O. Cirulli, Mohit Butaney, Sohrab Arora, Shane Tinsley, Patrick Etta, Akshay Sood, Giuseppe Carrieri, Alberto Briganti, Francesco Montorsi, Giovanni Lughezzani, Nicolò Buffi, Craig Rogers, and Firas Abdollah Giuseppe ChiarelliGiuseppe Chiarelli , Alex StephensAlex Stephens , Marco FinatiMarco Finati , Giuseppe O. CirulliGiuseppe O. Cirulli , Mohit ButaneyMohit Butaney , Sohrab AroraSohrab Arora , Shane TinsleyShane Tinsley , Patrick EttaPatrick Etta , Akshay SoodAkshay Sood , Giuseppe CarrieriGiuseppe Carrieri , Alberto BrigantiAlberto Briganti , Francesco MontorsiFrancesco Montorsi , Giovanni LughezzaniGiovanni Lughezzani , Nicolò BuffiNicolò Buffi , Craig RogersCraig Rogers , and Firas AbdollahFiras Abdollah View All Author Informationhttps://doi.org/10.1097/01.JU.0001009552.62973.71.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Black men have worse outcomes from prostate cancer (PCa) compared to White men. This is, at least partially, due to the racial disparity and health care delivery. Our aim was to evaluate the impact of race on surveillance intensity and Prostate Cancer Specific Mortality (PCSM) in patients on AS for PCa in a contemporary, real-world North American cohort. METHODS: We utilized our institutional database which was built by interrogating our electronic medical records for all men who got diagnosed with PCa within Henry Ford Health. Our cohort included White and Black men aged2 was reported in 44.1% of Black patients and 31.2% of White patients (p<0001). Median PSA at diagnosis was 5.7 (4.6-8.0) ng/ml in Black patients and 5.0 (4.0-6.6) ng/ml in White patients (p<0.0001). The rate of GG 2 was higher in Black than in White patients (43,6% vs 30.1%, p<0.0001). Follow-up time was 6 years (2.5-9.6). Median PSAs testing/years after diagnosis was 1.4 (0.6-2.5) for Black patients and 1.6 (0.6-3.2) for Black patients (p<0.05). The rate of patients who underwent more than one biopsy after diagnosis was 14.6% of Black and 22.6% of White patients (p<0.001). In the overall period, PCSM was 4.1% in Black and 1.6% in White patients (p<0.01). The cumulative incidence of PCSM at 10 years was double for Black patients compared to White patients (5.2% vs 2.6% CI 95%, p=0.0502). At MVA Black patients had 2.1 folds higher PCSM than White patients (p=0.08). CONCLUSIONS: Black patients on AS tend to have more aggressive disease at diagnosis and seem to undergo less PSA testing and post-diagnosis biopsies. This might, at least partially, be explained by higher PCSM in Black patients on AS that we observed in our cohort. Our report is one of few examining the intensity and outcomes of AS in real-world practice with a focus on racial disparities. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e263 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Giuseppe Chiarelli More articles by this author Alex Stephens More articles by this author Marco Finati More articles by this author Giuseppe O. Cirulli More articles by this author Mohit Butaney More articles by this author Sohrab Arora More articles by this author Shane Tinsley More articles by this author Patrick Etta More articles by this author Akshay Sood More articles by this author Giuseppe Carrieri More articles by this author Alberto Briganti More articles by this author Francesco Montorsi More articles by this author Giovanni Lughezzani More articles by this author Nicolò Buffi More articles by this author Craig Rogers More articles by this author Firas Abdollah More articles by this author Expand All Advertisement PDF downloadLoading ...