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Trending in cardiology
Updated 6:22 AM UTC
Rank
Paper
Published
Coverage
1
Interleukin-6 Inhibition with Ziltivekimab for Atherosclerotic Disease
New England Journal of Medicine· Ridker P et al.
Nov 7
2
Coronary CT Angiography versus Intravascular Ultrasound Guidance for PCI
New England Journal of Medicine· Collet C et al.
Nov 1
EditorialPodcast
Coverage details
Editorial: ACC Journal Scan
Podcast: Nov 06, 2026 This Week in Cardiology
3
Left Bundle-Branch Pacing versus Right Ventricular Pacing for Atrioventricular Block
New England Journal of Medicine· Qian Z et al.
Nov 8
4
Pelacarsen and Cardiovascular Outcomes in Patients with High Lipoprotein(a)
New England Journal of Medicine· Cho L et al.
Nov 7
5
Community and EMS Interventions to Improve Survival in Cardiac Arrest
New England Journal of Medicine· Hansen C et al.
Nov 8
6
Plozasiran for Severe Hypertriglyceridemia and Risk of Pancreatitis
New England Journal of Medicine· Watts G et al.
Nov 4
7
TAVR in Patients with Moderate Aortic Stenosis with At-Risk Features
New England Journal of Medicine· Généreux P et al.
Nov 2
300 likes12 news
EditorialPodcast
Coverage details
Editorial: NEJM
Podcast: Nov 06, 2026 This Week in Cardiology
8
Statin–Ezetimibe Combination Therapy versus Statin Monotherapy in Atherosclerotic Cardiovascular Disease: A Prespecified Secondary Analysis of the Randomized Ez-PAVE Trial
Circulation· Lee S et al.
Nov 7
9
Intensive Blood-Pressure Lowering in Patients with Type 2 Diabetes
New England Journal of Medicine· Santo K et al.
Nov 7
10
Extended Analyses of Pelacarsen and Cardiovascular Outcomes in Patients with High Lipoprotein(a)
NEJM Evidence· Nissen S et al.
Nov 7
11
Discontinuing Statins in Older Adults without Cardiovascular Disease
New England Journal of Medicine· Rodondi N et al.
Nov 7
12
1-Year Safety and Effectiveness of a Next-Generation Dual-Seal Left Atrial Appendage Occluder
JACC: Cardiovascular Interventions· Lakkireddy D et al.
Nov 1
13
Effectiveness of Radiofrequency Renal Denervation in the United States: Six-Month Primary End Point Results From the SPYRAL AFFIRM Study
Circulation Cardiovascular Interventions· Kandzari D et al.
Nov 3
14
Multimodality Cardiac Imaging Substudy of the DAPT-SHOCK-AMI Randomized Trial: Echocardiographic and Cardiac Magnetic Resonance Assessment of Cangrelor versus Crushed Ticagrelor in Cardiogenic Shock Complicating Acute Myocardial Infarction
Circulation· Motovska Z et al.
Nov 7
15
Intensive Blood-Pressure Control in Patients with Previous Ischemic Stroke
New England Journal of Medicine· Silva G et al.
Nov 7
17
Percutaneous Transcatheter Mitral Valve Replacement for Symptomatic Mitral Regurgitation
Journal of the American College of Cardiology· Webb J et al.
Nov 1
19
Prehospital Extracorporeal Life Support in Refractory Out-of-Hospital Cardiac Arrest
New England Journal of Medicine· Miranda D et al.
Nov 7
20
Transcatheter Aortic Valve Replacement in Pure Aortic Regurgitation: The Randomized SEASON-AR Clinical Trial
Circulation· Gao X et al.
Oct 31
54 likes3 news
21
Milvexian with Antiplatelet Therapy after Acute Coronary Syndrome Event
New England Journal of Medicine· Gibson C et al.
Aug 29
22
Intravenous Thrombolysis for Acute Ischemic Stroke — New Directions
New England Journal of Medicine· Grotta J et al.
Nov 4
23
Single vs Double ProGlide Devices for Access Site Closure after Transfemoral Aortic Valve Replacement
Journal of the American College of Cardiology· Liu X et al.
Nov 1
24
Oct 26
25
3-Year Comparison of Sirolimus- Versus Paclitaxel-Coated Balloon Angioplasty in Femoropopliteal Artery Disease
JACC: Cardiovascular Interventions· Teichgräber U et al.
Nov 1
Editorial
Coverage details
Editorial: ACC Journal Scan (X)
27
Moderate Aortic Stenosis with At-Risk Features
Journal of the American College of Cardiology· Généreux P et al.
Nov 1
28
Immediate Ambulatory Electrocardiographic Monitoring in Syncope
New England Journal of Medicine· Reed M et al.
Aug 30
10 likes10 news
EditorialPodcast
Coverage details
Editorial: NEJM
Podcast: Oct 30 2026 This Week in Cardiology
29
Early Increases in GDF-15 Are Associated With Declines in Cardiac Function With Breast Cancer Therapy
JACC Advances· Wilcox N et al.
Nov 1
Editorial
Coverage details
Editorial: ACC Journal Scan (X)
30
Discontinuing Statins in Older Adults without Cardiovascular Disease
New England Journal of Medicine· Rodondi N et al.
Nov 7
25 likes2 news
31
Prevalence of Silent Atherosclerosis across Adult Life
New England Journal of Medicine· Bundgaard H et al.
Aug 29
32
Efficacy and Safety of Routine Postdilation in Balloon-Expandable Transcatheter Aortic Valve Implantation Platform
JAMA Cardiology· Autherith M et al.
Nov 3
33
ANGPTL4 Inhibition in Adults with Elevated Triglyceride Levels
New England Journal of Medicine· O’Donoghue M et al.
Nov 9
34
Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis
New England Journal of Medicine· Bundgaard H et al.
Aug 28
47 likes7 news
EditorialPodcast
Coverage details
Editorial: ACC Journal Scan (X)
Podcast: Oct 02 2026 This Week in Cardiology
35
Hematopoietic loss of KDM6A impairs cardiac recovery in heart failure via epigenetic reprogramming of myeloid cells
Nature Cardiovascular Research· Solomonidis E et al.
Nov 3
1 news
36
2026 SCAI SHOCK Classification Expert Consensus Update: Refined Staging and Incorporation of Clinical Phenotypes and Patient Populations
Journal of the Society for Cardiovascular Angiography & Interventions· Baran D et al.
Nov 1
185 likes5 news
38
Targeted Use of Computed Tomographic Coronary Angiography in Acute Chest Pain
New England Journal of Medicine· Lee K et al.
Aug 29
55 likes7 news
EditorialPodcast
Coverage details
Editorial: ACC Journal Scan
Podcast: Sep 11 2026 This Week in Cardiology
39
Interpreting High-Sensitivity Cardiac Troponin in Clinical Practice and Emerging Directions
Journal of the American College of Cardiology· Spanos M et al.
Oct 1
40
Reproductive factors in women with familial hypercholesterolaemia
European Journal of Preventive Cardiology· Mulder J et al.
Oct 2
2 news
Editorial
Coverage details
Editorial: ESC Press Release
41
Long-Term Survival After Initial Invasive or Conservative Management of Stable Coronary Disease in Patients With Advanced Chronic Kidney Disease: ISCHEMIA-CKD EXTEND
Circulation· Bangalore S et al.
Nov 7
2 likes3 news
42
Performance of 0/1 h versus 0/3 h pathways in patients with suspected myocardial infarction: a systematic review and individual participant data meta-analysis of randomised controlled trials
The Lancet· Boeddinghaus J et al.
Oct 1
44
Selective blockade of microRNA-31-5p−calcitonin receptor interaction reverses established atrial fibrosis and atrial arrhythmia burden
Nature Cardiovascular Research· Trompf* J et al.
Oct 30
9 news
45
10-Year Outcomes of Initial CTO-PCI Versus No CTO-PCI Strategies for Chronic Total Occlusion: The DECISION-CTO Randomized Trial
Journal of the American College of Cardiology· Kim J et al.
Nov 1
Podcast
Coverage details
Podcast: Nov 06, 2026 This Week in Cardiology
46
Long-Term Survival After Initial Invasive or Conservative Management of Stable Coronary Disease in ISCHEMIA-EXTEND
JAMA· Hochman J et al.
Nov 7
9 news
47
Thirty-Day Outcomes of a Dedicated Transcatheter Occlusion Device for Paravalvular Leak Closure: The PARADIGM Study
JACC: Cardiovascular Interventions· Cruz‐González I et al.
Oct 1
48
Optimizing Echocardiographic Evaluation of Chronic Mitral Regurgitation
JACC. Cardiovascular imaging· El-Tallawi K et al.
Oct 1
Editorial
Coverage details
Editorial: ACC Journal Scan
49
Deep learning-enabled assessment of right ventricular size and function is associated with cardiovascular outcomes
Nature Cardiovascular Research· Al‐Alusi M et al.
Oct 15
No coverage recorded
50
Real-world comparative effectiveness of evolocumab versus ezetimibe in adults with atherosclerotic cardiovascular disease: an active-comparator new-user study
American Journal of Preventive Cardiology· Desai N et al.
Nov 1
21 likes5 news
Evidence-backed clinical questions
- Does sglt2 inhibitors vs dpp-4 inhibitors improve All-Cause Hospitalization in Diabetes Mellitus, Type 2? — 2 studies (35,860 patients) provide low-certainty evidence for benefit of sglt2 inhibitors for All-Cause Hospitalization in Diabetes Mellitus, Type 2.
- Does asparaginase vs placebo improve outcomes in L2 Acute Lymphoblastic Leukemia? — 4 studies (221 patients) provide low-certainty evidence against benefit of asparaginase for Myocardial Infarction Hospitalization in L2 Acute Lymphoblastic Leukemia.
- Does phenylephrine vs placebo improve Systolic Blood Pressure? — 2 studies (45 patients) provide low-certainty evidence against benefit of phenylephrine for Systolic Blood Pressure in this population.
- Does amiodarone vs placebo improve outcomes in Atrial Fibrillation? — 60 studies (461,152 patients, 7 RCTs) provide moderate-certainty evidence against benefit of amiodarone for Myocardial Infarction Hospitalization in Atrial Fibrillation.