Abstract Background Cardiac magnetic resonance imaging (CMR) is the gold standard for evaluating adult congenital heart disease (ACHD), but conventional protocols are time-consuming. Objective This study aimed to validate 3D cine (ESSOS) and 4D-flow MRI compared with standard 2D cine and 2D flow techniques in ACHD patients. Methods Eligible ACHD patients (≥18 years) underwent standard 2D cine and 2D flow imaging, followed by 3D cine (ESSOS) and 4D flow acquisitions using a 3.0T MRI system. Ventricular volumes, function, and flow parameters were assessed, with comparisons made using intraclass correlation coefficients (ICC) and Bland-Altman analysis. Results Eleven patients completed both advanced sequences. ESSOS showed excellent agreement with 2D cine for stroke volume (ICC = 0.964) and LV mass (ICC = 0.936), with good agreement for most volume metrics in same scan time (7.2 vs. 8.1 minutes). LVEF and RVEF showed moderate to poor agreement. 4D-flow imaging also halved acquisition time versus 2D flow (7.5 vs. 15.9 minutes) and demonstrated good to excellent agreement with 2D flow for ascending aorta (ICC = 0.844) and pulmonary artery flow (ICC = 0.959). Conclusion ESSOS and 4D-flow are accurate, time-efficient alternatives to conventional techniques, supporting their integration into CMR protocols for ACHD assessment.Intraclass Correlation Bland altman plot
Lertnimittham et al. (Thu,) studied this question.
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