Key result
Combined 3D cine and 4D-flow MRI cuts scan time ~53% with excellent agreement vs. 2D.
Why the study?
Do 3D cine (ESSOS) and 4D-flow MRI provide accurate and time-efficient cardiac function evaluation compared to standard 2D cine and 2D flow techniques in adult patients with congenital heart disease?
Observational (n=11)
Do 3D cine (ESSOS) and 4D-flow MRI provide accurate and time-efficient cardiac function evaluation compared to standard 2D cine and 2D flow techniques in adult patients with congenital heart disease?
3D cine (ESSOS) and 4D-flow MRI offer accurate and time-efficient alternatives to conventional 2D CMR techniques for evaluating adult congenital heart disease.
Background Cardiac magnetic resonance imaging (CMR) is the gold standard for evaluating adult congenital heart disease (ACHD), but conventional protocols are time-consuming. Objective This study aimed to validate 3D cine (ESSOS) and 4D-flow MRI compared with standard 2D cine and 2D flow techniques in ACHD patients. Methods Eligible ACHD patients (≥18 years) underwent standard 2D cine and 2D flow imaging, followed by 3D cine (ESSOS) and 4D flow acquisitions using a 3.0T MRI system. Ventricular volumes, function, and flow parameters were assessed, with comparisons made using intraclass correlation coefficients (ICC) and Bland-Altman analysis. Results Eleven patients completed both advanced sequences. ESSOS showed excellent agreement with 2D cine for stroke volume (ICC = 0.964) and LV mass (ICC = 0.936), with good agreement for most volume metrics in same scan time (7.2 vs. 8.1 minutes). LVEF and RVEF showed moderate to poor agreement. 4D-flow imaging also halved acquisition time versus 2D flow (7.5 vs. 15.9 minutes) and demonstrated good to excellent agreement with 2D flow for ascending aorta (ICC = 0.844) and pulmonary artery flow (ICC = 0.959). Conclusion ESSOS and 4D-flow are accurate, time-efficient alternatives to conventional techniques, supporting their integration into CMR protocols for ACHD assessment.
No takes yet. Share an insight, caveat, or question.
Lertnimittham et al. (2026) conducted an observational in Adult congenital heart disease (ACHD) (n=11). 3D cine (ESSOS) and 4D-flow MRI vs. Standard 2D cine and 2D flow techniques was evaluated on Ventricular volumes, function, and flow parameters. 3D cine (ESSOS) and 4D-flow MRI showed excellent agreement with 2D techniques for stroke volume (ICC=0.964) and pulmonary artery flow (ICC=0.959), with reduced scan times (7.5 vs 15.9 mins).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: