A Murine Model of HSV-1-Induced Corneal Endotheliitis: Primary Infection, Latency, and Recurrence | Synapse
March 1, 2026Open Access
A Murine Model of HSV-1-Induced Corneal Endotheliitis: Primary Infection, Latency, and Recurrence
Puntos clave
The aim is to establish a reliable murine model for studying HSV-1 induced corneal endotheliitis, including its infection phases.
Developed a murine model to simulate HSV-1 infection in corneal tissue.
Investigated phases of primary infection, latency, and recurrence in the model.
Used various assessments to analyze pathological mechanisms.
Successfully demonstrated phases of HSV-1 infection including latency and recurrence.
Provided insights into the pathological mechanisms involved in corneal endotheliitis.
Resumen
We successfully established a murine model of primary infection, latency and recurrence of HSV endotheliitis, providing a reliable platform for investigating pathological mechanisms and potential treatments.