Association Between Glymphatic Function and White Matter Microstructural Injury in Patients With Cushing's Disease.

Puntos clave

• To investigate the relationship between glymphatic function and white matter injury in patients with Cushing's disease.
• Observed cortisol levels at midnight in patients with Cushing's disease.
• Assessed glymphatic function through imaging techniques.
• Evaluated microstructural integrity of white matter pathways.
• Glymphatic function was impaired in patients with Cushing's disease.
• Elevated midnight cortisol levels were linked to glymphatic dysfunction.
• Impaired glymphatic function mediated the relationship with microstructural injury to the SLF III_R.