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PRRSV Nsp11 antagonizes host antiviral immune response by reducing OAS1 and RNase L expressions | Synapse
March 3, 2026
Open Access
PRRSV Nsp11 antagonizes host antiviral immune response by reducing OAS1 and RNase L expressions
DJ
Dandan Jiang
XW
Xiaoran Wang
CS
Chao Sui
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Puntos clave
Reductions in OAS1 and RNase L expressions are linked to the viral protein Nsp11.
PRRSV infected cells exhibit a significant decrease in host antiviral immunity markers.
The analysis utilized a quantitative approach to measure the expression levels of specific biomarkers.
These findings may enable better understanding of immune evasion strategies in viral infections.
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Jiang et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75e92c6e9836116a294e3
https://doi.org/https://doi.org/10.1186/s12917-026-05318-w
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