PRRSV Nsp11 antagonizes host antiviral immune response by reducing OAS1 and RNase L expressions

Key Points

• Reductions in OAS1 and RNase L expressions are linked to the viral protein Nsp11.
• PRRSV infected cells exhibit a significant decrease in host antiviral immunity markers.
• The analysis utilized a quantitative approach to measure the expression levels of specific biomarkers.
• These findings may enable better understanding of immune evasion strategies in viral infections.