Does body mass index predict aldosterone production in normotensive adults on a high-salt diet?
Increased aldosterone production in overweight normotensive adults correlates with insulin resistance, suggesting a potential role for aldosterone in obesity-mediated insulin resistance.
Urinary aldosterone excretion and AngII-stimulated aldosterone are increased in overweight, compared with lean, normotensive adults. The correlation of these measures of aldosterone production with insulin resistance suggests a potential role for aldosterone in the pathophysiology of obesity-mediated insulin resistance.
Bentley–Lewis et al. (Tue,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: