Why the study?
Does body mass index predict aldosterone production in normotensive adults on a high-salt diet?
Does body mass index predict aldosterone production in normotensive adults on a high-salt diet?
Increased aldosterone production in overweight normotensive adults correlates with insulin resistance, suggesting a potential role for aldosterone in obesity-mediated insulin resistance.
May link aldosterone to obesity-related insulin resistance; hypothesis-generating, needs prospective trials before practice change.
Urinary aldosterone excretion and AngII-stimulated aldosterone are increased in overweight, compared with lean, normotensive adults. The correlation of these measures of aldosterone production with insulin resistance suggests a potential role for aldosterone in the pathophysiology of obesity-mediated insulin resistance.
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Bentley–Lewis et al. (2007) studied this question.
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