Does the mDixon LGE sequence improve image quality compared to the PSIR sequence in patients with atrial fibrillation?
The mDixon LGE-CMR sequence provides superior image quality and contrast-to-noise ratio compared to the PSIR sequence for detecting left atrial fibrosis in patients with atrial fibrillation.
To compare image quality, agreement in left atrial fibrosis (LAF) quantification, and acquisition time for late gadolinium enhancement (LGE) imaging between three-dimensional whole-heart modified Dixon (mDixon) and phase-sensitive inversion recovery (PSIR) sequences of cardiac magnetic resonance (CMR) in patients with atrial fibrillation (AF). Thirty patients with AF who underwent LGE-CMR were prospectively enrolled. Subjective image quality scores, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), contrast ratio (CR), and acquisition time were compared, and inter-sequence agreement in LAF quantification was assessed. Compared with PSIR-LGE, mDixon-LGE achieved a higher rate of excellent image quality (80% vs. 60%, P = 0.031), higher CNR
Jiang et al. (Mon,) studied this question.