Why the study?
To compare image quality, agreement in left atrial fibrosis quantification, and acquisition time between 3D whole-heart mDixon and PSIR LGE-CMR sequences in patients with AF.
Does the mDixon LGE sequence improve image quality compared to the PSIR sequence in patients with atrial fibrillation?
Observational (n=30)
Does the mDixon LGE sequence improve image quality compared to the PSIR sequence in patients with atrial fibrillation?
Absolute Event Rate: 80% vs 60%
p-value: p=0.031
The mDixon LGE-CMR sequence provides superior image quality and contrast-to-noise ratio compared to the PSIR sequence for detecting left atrial fibrosis in patients with atrial fibrillation.
mDixon-LGE may enhance LA imaging in AF; leaves open whether superior quality improves fibrosis quantification.
To compare image quality, agreement in left atrial fibrosis (LAF) quantification, and acquisition time for late gadolinium enhancement (LGE) imaging between three-dimensional whole-heart modified Dixon (mDixon) and phase-sensitive inversion recovery (PSIR) sequences of cardiac magnetic resonance (CMR) in patients with atrial fibrillation (AF). Thirty patients with AF who underwent LGE-CMR were prospectively enrolled. Subjective image quality scores, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), contrast ratio (CR), and acquisition time were compared, and inter-sequence agreement in LAF quantification was assessed. Compared with PSIR-LGE, mDixon-LGE achieved a higher rate of excellent image quality (80% vs. 60%, P = 0.031), higher CNR
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Jiang et al. (2026) conducted an observational in Atrial fibrillation (n=30). mDixon-LGE vs. PSIR-LGE was evaluated on Excellent image quality (p=0.031).
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