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The m5C demethylase TET1 is identified as a key regulator of scleral remodeling in myopia | Synapse

March 12, 2026Open Access

The m5C demethylase TET1 is identified as a key regulator of scleral remodeling in myopia

Puntos clave

This research aims to identify the role of TET1 in scleral remodeling associated with myopia.
Analyzed TET1 expression levels in myopic sclera
Examined m5C modifications in scleral tissue
TET1 expression is significantly altered in myopic sclera
m5C modifications are also altered, indicating its role in scleral remodeling

Resumen

Our study reveals substantial alterations in TET1 expression and m5C modification in myopic sclera, providing new insights that may inform the development of novel diagnostic and therapeutic approaches for myopia management.

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Cite This Study

Jia et al. (Mon,) studied this question.

synapsesocial.com/papers/69b2585696eeacc4fcec7e1b https://doi.org/https://doi.org/10.1186/s13148-026-02099-9

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