Characterisation of the Novel HLA-DRB1*13:370N Allele by Next-Generation Sequencing.

Puntos clave

• The research aims to characterize the novel HLA-DRB1*13:370N allele and its genetic variations.
• Utilized next-generation sequencing to analyse the HLA-DRB1 allele.
• Identified nucleotide deletions in the allele's coding region.
• Focused on variations in codon 77 in exon 2.
• HLA-DRB1*13:370N shows a deletion of two nucleotides at codon 77.
• This deletion differentiates it from HLA-DRB1*13:01:01:01.