Functionalisation of homopropargyl boronic esters via hydrozirconation followed by Pd-catalysed cross coupling reaction | Synapse
March 26, 2026Open Access
Functionalisation of homopropargyl boronic esters via hydrozirconation followed by Pd-catalysed cross coupling reaction
Puntos clave
The aim is to explore the functionalisation of homopropargyl boronic esters using hydrozirconation and cross coupling.
Utilization of hydrozirconation for reactive functionalisation.
Application of Pd-catalysed cross coupling reactions.
Synthesis of homopropargyl boronic esters via Matteson homologation.
Successful selective functionalisation of homopropargyl boronic esters.
Retention of boronic ester functionality during the reaction.
Resumen
Hydrozirconation of homopropargyl boronic esters accessible via Matteson homologation allows their selective functionalisation while retaining the boronic ester functionality.