The aim is to explore the functionalisation of homopropargyl boronic esters using hydrozirconation and cross coupling.
Utilization of hydrozirconation for reactive functionalisation.
Application of Pd-catalysed cross coupling reactions.
Synthesis of homopropargyl boronic esters via Matteson homologation.
Successful selective functionalisation of homopropargyl boronic esters.
Retention of boronic ester functionality during the reaction.
Abstract
Hydrozirconation of homopropargyl boronic esters accessible via Matteson homologation allows their selective functionalisation while retaining the boronic ester functionality.