Does higher beta blocker dose reduce mortality in heart failure patients?
In heart failure patients, higher beta blocker doses are associated with lower mortality, and cardiac 123 I-mIBG uptake serves as a powerful prognostic marker.
Higher beta blocker dose was associated with lower mortality, but of the variables associated with sympathetic activity examined, cardiac 123 I-mIBG uptake was the most powerful prognostic marker in heart failure patients. Elevated heart rate was associated with greater risk for cardiac death.
Cohen‐Solal et al. (Wed,) studied this question.