Does high-rate or delayed ICD programming reduce inappropriate therapy and all-cause mortality compared with conventional programming?
Programming ICDs for higher rate thresholds or prolonged delays safely reduces inappropriate therapies and improves overall survival compared to conventional programming.
Programming of ICD therapies for tachyarrhythmias of 200 beats per minute or higher or with a prolonged delay in therapy at 170 beats per minute or higher, as compared with conventional programming, was associated with reductions in inappropriate therapy and all-cause mortality during long-term follow-up. (Funded by Boston Scientific; MADIT-RIT ClinicalTrials.gov number, NCT00947310.).
Moss et al. (Tue,) studied this question.
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