February 25, 2011Open Access

Human Atherosclerotic Plaque Alternative Macrophages Display Low Cholesterol Handling but High Phagocytosis Because of Distinct Activities of the PPARγ and LXRα Pathways

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Resumen

These data identify a distinct macrophage subpopulation with a low susceptibility to become foam cells but high phagocytic activity resulting from different regulatory activities of the PPARγ-LXRα pathways.

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Chinetti et al. (Fri,) studied this question.

synapsesocial.com/papers/69d73a1d35079b684748f4e6 https://doi.org/https://doi.org/10.1161/circresaha.110.233775

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5MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis1991 · 3,277 citations

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