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February 25, 2011Circulation ResearchOpen Access

Human Atherosclerotic Plaque Alternative Macrophages Display Low Cholesterol Handling but High Phagocytosis Because of Distinct Activities of the PPARγ and LXRα Pathways

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Abstract

These data identify a distinct macrophage subpopulation with a low susceptibility to become foam cells but high phagocytic activity resulting from different regulatory activities of the PPARγ-LXRα pathways.

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Cite This Study

Chinetti et al. (2011) studied this question.

synapsesocial.com/papers/69d73a1d35079b684748f4e6 https://doi.org/10.1161/circresaha.110.233775

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