June 22, 2017

Management of Oral Anticoagulation Therapy After Gastrointestinal Bleeding: Whether to, When to, and How to Restart an Anticoagulation Therapy

PICO estructurado

Población

Patients who experienced gastrointestinal bleeding (GIB) while on oral anticoagulation therapy

Intervención

Resumption of oral anticoagulation therapy (warfarin or DOACs, specifically apixaban) between 7 and 14 days following GIB

This review recommends restarting oral anticoagulation 7 to 14 days after a gastrointestinal bleed, highlighting apixaban as a potentially preferred DOAC.

Resumen

Anticoagulation therapy resumption is recommended, with resumption being considered between 7 and 14 days following GIB regardless of the therapy chosen. Data for warfarin management after GIB should be applied with caution to direct oral anticoagulants (DOACs) because of the quicker onset and experimental nature of reversal agents. Apixaban may be a preferred option when restarting a DOAC therapy.

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Cite This Study

Kido et al. (Thu,) studied this question.

synapsesocial.com/papers/69da87ab8988aeabbe686f10 https://doi.org/https://doi.org/10.1177/1060028017717019

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