January 1, 2007Open Access

Isoflurane Provides Long-term Protection against Focal Cerebral Ischemia in the Rat

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Resumen

Isoflurane repeatedly improved long-term neurologic and histologic outcome from focal ischemia independent of ischemia duration, perfusion pressure, or pretreatment with 5-hydroxydecanoate.

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Cite This Study

Sakai et al. (Mon,) studied this question.

synapsesocial.com/papers/69dd46db8557d5ab8f40c7cf https://doi.org/https://doi.org/10.1097/00000542-200701000-00017

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2A Comparison of the Cerebral Protective Effects of Isoflurane and Barbiturates during Temporary Focal Ischemia in Primates1987 · 148 citations
3Opening of Mitochondrial ATP-Sensitive Potassium Channels Is a Trigger of 3-Nitropropionic Acid–Induced Tolerance to Transient Focal Cerebral Ischemia in Rats2003 · 85 citations
4Effects of Halothane on Regional Cerebral Blood Flow in Experimental Focal Ischemia1973 · 21 citations
5Preconditioning with Isoflurane Produces Dose-Dependent Neuroprotection via Activation of Adenosine Triphosphate-Regulated Potassium Channels After Focal Cerebral Ischemia in Rats2003 · 178 citations

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