Pulse Explorar nav.journalClub Debates Tendencias Investigadores Revistas

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

Inicio Explorar nav.journalClub Tendencias

⌘+K

Trem2 deletion enhances tau dispersion and pathology through microglia exosomes | Synapse

September 2, 2022Open Access

Trem2 deletion enhances tau dispersion and pathology through microglia exosomes

BZBing ZhuTongji University YLYan LiuCarrier (United States)SHSpring HwangThe University of Texas MD Anderson Cancer Center

Puntos clave

Los puntos clave no están disponibles para este artículo en este momento.

Resumen

Together, our results reveal a role for Trem2 in suppressing exosomal tau pathogenicity, and demonstrates that Trem2 deletion can enhance tau trafficking, distribution and seeding through microglial exosomes.

Preguntar a la IA

Me gusta

Guardar

Compartir

Ver artículo completo

Cite This Study

Zhu et al. (Fri,) studied this question.

synapsesocial.com/papers/69dd49050644c7b49d40ca32 https://doi.org/https://doi.org/10.1186/s13024-022-00562-8

Preguntar a la IA

Me gusta

Guardar

Compartir

Ver artículo completo