March 2, 2018

Sedation Intensity in the First 48 Hours of Mechanical Ventilation and 180-Day Mortality: A Multinational Prospective Longitudinal Cohort Study*

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Resumen

Sedation intensity independently, in an ascending relationship, predicted increased risk of death, delirium, and delayed time to extubation. These observations suggest that keeping sedation level equivalent to a Richmond Agitation Sedation Scale 0 is a clinically desirable goal.

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Cite This Study

Shehabi et al. (Fri,) studied this question.

synapsesocial.com/papers/69de85e1210a0977fce9496a https://doi.org/https://doi.org/10.1097/ccm.0000000000003071

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1ICU Physicians' Perception of Patients' Tolerance Levels in Light Sedation Impacts Sedation Practice for Mechanically Ventilated Patients2019 · 6 citations
2Daily Interruption of Sedative Infusions in Critically Ill Patients Undergoing Mechanical Ventilation2000 · 2,975 citations
3Validation of the Critical-Care Pain Observation Tool in Adult Patients2006 · 709 citations
4Dexmedetomidine vs Midazolam or Propofol for Sedation During Prolonged Mechanical Ventilation2012 · 967 citations
5Staff education, regular sedation and analgesia quality feedback, and a sedation monitoring technology for improving sedation and analgesia quality for critically ill, mechanically ventilated patients: a cluster randomised trial2016 · 52 citations

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