April 1, 1994Open Access
Ver artículo completoDose-response of chronic beta-blocker treatment in heart failure from either idiopathic dilated or ischemic cardiomyopathy. Bucindolol Investigators.
Puntos clave
- This research aims to evaluate the dose-response relationship of chronic beta-blocker treatment with bucindolol in heart failure patients.
- Investigated the effects of chronic beta-blocker therapy using bucindolol.
PICO estructurado
Does chronic beta-blocker treatment with bucindolol improve left ventricular function in patients with heart failure from systolic dysfunction?
P
Población
Patients with heart failure from systolic dysfunction (idiopathic dilated or ischemic cardiomyopathy)
I
Intervención
Bucindolol (chronic beta-blocker treatment)
O
Resultado
Left ventricular functionsurrogate
Bucindolol provides a dose-dependent improvement in left ventricular function in patients with heart failure due to systolic dysfunction.
Resumen
In heart failure from systolic dysfunction, beta-blockade with bucindolol produces a dose-related improvement in and prevents deterioration of left ventricular function.