Does dobutamine challenge aid in selecting patients with low-output, low-gradient aortic stenosis and depressed left ventricular systolic function who would benefit from an aortic valve operation?
Dobutamine challenge may help identify patients with low-output, low-gradient aortic stenosis and LV dysfunction who will benefit from aortic valve surgery.
In patients with left ventricular systolic dysfunction and aortic stenosis with a low output and a low mean gradient, dobutamine challenge may aid in selecting those who would benefit from an aortic valve operation.
Nishimura et al. (2002) studied this question.