Why the study?
Does dobutamine challenge aid in selecting patients with low-output, low-gradient aortic stenosis and depressed left ventricular systolic function who would benefit from an aortic valve operation?
Does dobutamine challenge aid in selecting patients with low-output, low-gradient aortic stenosis and depressed left ventricular systolic function who would benefit from an aortic valve operation?
Dobutamine challenge may help identify patients with low-output, low-gradient aortic stenosis and LV dysfunction who will benefit from aortic valve surgery.
Answers are grounded in this paper and cite their sources.
May support dobutamine testing in low-flow low-gradient AS; hypothesis-generating and should not yet change practice.
In patients with left ventricular systolic dysfunction and aortic stenosis with a low output and a low mean gradient, dobutamine challenge may aid in selecting those who would benefit from an aortic valve operation.
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Nishimura et al. (2002) studied this question.
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