Cardiac resynchronization therapy in patients with HFrEF normalized altered monocyte composition to levels observed in controls without HFrEF (P=0.003).
Observational (n=108)
Does cardiac resynchronization therapy normalize altered monocyte composition in patients with stable HFrEF?
Cardiac resynchronization therapy may reverse the altered monocyte composition seen in patients with stable HFrEF, restoring it to levels observed in healthy controls.
valor p: p=0.003
BACKGROUND: ) in HFrEF patients and to assess the effect of the cardiac resynchronization therapy (CRT) on the changes in monocyte compartment. METHODS: The study included 85 patients with stable HFrEF. Twenty-five of them underwent CRT device implantation with subsequent 6-month assessment. The control group consisted of 23 volunteers without HFrEF. RESULTS: = 0.003). CONCLUSIONS: HFrEF patients present altered monocyte composition. CRT-related changes in the monocyte compartment achieve levels observed in controls without HFrEF.
Ptaszyńska‐Kopczyńska et al. (Thu,) conducted a observational in Chronic Heart Failure with reduced Ejection Fraction (HFrEF) (n=108). Cardiac resynchronization therapy (CRT) vs. Volunteers without HFrEF was evaluated on Changes in monocyte compartment (p=0.003). Cardiac resynchronization therapy in patients with HFrEF normalized altered monocyte composition to levels observed in controls without HFrEF (P=0.003).
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